Ultra Liquid Chromatography Mass Spectroscopy (ULCMS) is an advanced analytical technique that combines Ultra-High-Performance Liquid Chromatography (UHPLC) with Mass Spectrometry (MS).
Liquid Chromatography-Mass Spectroscopy (LCMS) is a powerful analytical technique that combines High-Performance Liquid Chromatography (HPLC) with Mass Spectrometry (MS) for the detection, separation, identification, and quantification of chemical compounds.
Liquid Chromatography with Low Non-Volatile Residue (LCN) is a specialized form of Liquid Chromatography (LC) designed for applications that require ultra-high purity solvents and minimal contamination from non-volatile residues (NVRs).
High-Performance Liquid Chromatography (HPLC) is an advanced analytical technique used for the separation, identification, and quantification of compounds in complex mixtures.
Gas Chromatography-Mass Spectroscopy (GC-MS) is a powerful analytical technique that combines Gas Chromatography (GC) for separating volatile compounds with Mass Spectrometry (MS) for identifying and quantifying them.
Gas Chromatography-Headspace (GC-HS) is a technique used to analyze volatile and semi-volatile compounds in solid or liquid samples without direct injection.
Liquid Chromatography-Mass Spectrometry (LC-MS) requires carefully selected additives to optimize ionization, improve peak shape, and enhance sensitivity for precise quantification and identification of analytes.
High-Performance Liquid Chromatography (HPLC) requires buffers to maintain pH stability, improve peak shape, and enhance reproducibility. Choosing the right buffer depends on pH range, volatility (for MS compatibility), and solubility in the mobile phase.
Ion-pairing chromatography is used in reversed-phase HPLC (RP-HPLC) to enhance the retention and separation of highly polar or ionic compounds (e.g., acids, bases, nucleotides, peptides). Ion-pairing reagents interact with analytes, modifying their hydrophobicity and enabling better retention on non-polar columns.
